Beyond the randomized clinical trials comes the real-world evidence

Sofia, November 14, 2022 – Dr. Gergana Shalamanova from the Oncology Center in Plovdiv showed the interesting comparison of Real-world Evidence (RWE) vs. Randomized Clinical Trials at the Second National Congress in Dermatooncology.

The results of BRAF inhibitors’ registrational clinical trials have been externally validated to the real-world population of patients with BRAF+ melanoma using Sqilline Danny Platform.

The efficacy of certain targeted therapies in BRAF+ melanoma patients is better in real-world settings compared to the results of two randomized clinical trials with differences of:

  • 20 and 24% in progression-free survival (PFS) at 12 months;
  • 12 and 13% in overall survival (OS) at 12 months.

Beyond the randomized clinical trials comes the real-world evidence… Danny Platform compares both and shows higher efficacy of targeted therapies in real-world BRAF+ melanoma patients,” said Dr. Shalamanova.

These findings open discussion for the wider use of technology in generating Real-world Evidence (RWE) to assess treatment outcomes in real-world settings.

Sqilline Danny Platform proves to be a highly effective technology to collect, process, and analyze Real-world Data (RWD) from Electronic Health Records (EHRs) and turning it into RWE.

Curious to learn more? Get in touch with our team! https://sqilline.com/contact-us/

Share this article:

More News & Highlights

News

First patients diagnosed with rare disease with assist of AI algorithm are fact in Bulgaria

Sqilline and a leading pharmaceutical company have partnered to apply AI algorithm and track for high-risk patients for the rare disease of Transthyretin amyloid polyneuropathy...

Read more...

Job Offer

Sqilline is looking for Key Account Manager Hospitals/Physicians

Company description Sqilline is a software and Clinical Research Organisation (CRO) that expertise in Big Data technology, machine learning algorithms, and AI. The company has built...

Read more...

News

How technology can support Scientific Research in medicine?

Varna, October 22, 2022 - Sqilline was thrilled to attend the yearly National Oncology Conference СОНМ-МОРЕ 2022. During the expert session on Digital Reconstruction in Bulgarian...

Read more...