Advances in Therapy, an international medical journal, has published the Research Article “Familial Hypercholesterolemia identification algorithm in patients with acute cardiovascular event in a large hospital electronic database in Bulgaria – a call for implementation”
Sqilline is extremely honored to be co-writer among such extreme professionals and experts in the field.
Our advanced solution Danny Platform® played a key role in the process and analyses of this fundamental article.
Click to play the abstract video of the article:
KEY SUMMARY POINTS:
OBJECTIVES:
- Using all available medical records from EHR systems to extract treated patients admitted for ASCVD acute events to screen for FH
- Reinforce early FH identification and improving patient pathways and outcomes
CHALLENGES:
- Limited data on the proportion and management of FH among adults
- Under diagnosed, an acute event is usually the 1st clinical manifestation of FH
- Most patients are unaware they have it until a significant cardio event occures
SOLUTION:
- Danny Platform’s NLP algorithm was developed to identify patients with arcus Cornealis, tendon xanthoma, or stated FH
- Danny Platform’s algorithms search the EHR of patients admitted to hospital for the treatment of an acute CV event to identify those with undiagnosed FH
- The platform can automatically calculate the Dutch Lipid Clinic Network Score(DLCNS)
RESULTS:
- 11 090 patients recorded an acute cardiovascular event
- 44% of patients to have possible FH and 56% to have probable/definite FH
- 37% of patients discharged with high-intensity satin therapy
- 96% of patients had poorly controlled cholesterol during the first year after discharge
BENEFITS
- Systematic screening and early identification of FH during hospitalization will improve patients’ treatment and outcomes
- Empowering physicians to reinforcing early FH identification to improve futurepatient outcomes
- Reducing burden on the healthcare system via automated screening tool during hospitalization may allow for rapid and effective lipid management, prevention of recurrent events
ARTICLE AUTHORS:
- Prof. Ivo Petrov (Head of Cardiology, Angiology and Electrophysiology Department: Acibadem City Clinic Cardiovascular Center)
- Assos. Prof. Arman Postadzhiyan (Department of General Medicine, Emergency University Hospital “St. Anna”, Medical University of Sofia)
- Dr. Dobrin Vasilev (Head Cardiology Clinic at Alexandrovska University Hospital)
- Dr. Ruslan Kasabov (Department of Interventional Cardiology: Hospital “Pulmed” Plovdiv
- Prof. Dr. Fedya Nikolov and Assos. Prof. Mariya Tokmakova (Department of Cardiology, Medical University of Plovdiv)
- Reneta Petkova (Department of General Medicine, Amgen Bulgaria)
- Veselin Istatkov, Boyang Zhao, and Dimiter Mutafchiev (Sqilline)
Click here to read the full publication in Advances in Therapy: